Erythropoietin attenuated vascular dysfunction and inflammation by inhibiting NADPH oxidase-derived superoxide production in nitric oxide synthase-inhibited hypertensive rat aorta

Endothelial dysfunction in rat adjuvant-

Endothelial dysfunction in rat adjuvant-induced arthritis: Vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase

✍ Yoshisuke Haruna; Yoshitaka Morita; Norio Komai; Toyotaka Yada; Takeo Sakuta; Na 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 141 KB 👁 2 views

## Abstract ## Objective To investigate endothelial function and levels of vascular oxidative stress in rat adjuvant‐induced arthritis (AIA), in view of mounting evidence for an association between rheumatoid arthritis (RA) and accelerated vascular disease. ## Methods Thoracic aortic rings were