Erythrocytosis and renal cell carcinoma with pulmonary metastases: Case report with 18-year followup and brief discussion of literature

A Phase Ib/II trial of granulocyte-macro

A Phase Ib/II trial of granulocyte-macrophage−colony stimulating factor and interleukin-2 for renal cell carcinoma patients with pulmonary metastases : A case of fatal central nervous system thrombosis

✍ Kirsten M. Hotton; Masoud Khorsand; Jacquelyn A. Hank; Mark Albertini; Kyung Man 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 187 KB 👁 2 views

## BACKGROUND. Interleukin-2 (IL-2) and granulocyte-macrophageϪcolony stimulating factor (GM-CSF) are cytokines with nonoverlapping pleiotropic effects. In a prior Phase Ib study, this combination of agents exhibited antitumor effects in the lungs of four of eight patients with renal cell carcinoma