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Erythrocyte glutathione peroxidase deficiency: Biochemical studies on the mechanisms of drug-induced hemolysis

✍ Scribed by Martin H. Steinberg; Thomas F. Necheles


Book ID
115675907
Publisher
Elsevier Science
Year
1971
Tongue
English
Weight
469 KB
Volume
50
Category
Article
ISSN
1555-7162

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## Abstract The haloacetonitrile, dibromoacetonitrile (DBAN), is a direct‐acting genotoxic agent that has been detected in drinking water. In a time course study, male Sprague‐Dawley rats were treated with DBAN (75 mg/kg PO), and killed at 0.5, 1, 2, and 4 hr after treatment. In a dose response stu