erythro-2-Piperidinyl-1,2-diphenylethanol
✍ Scribed by Ocak, Nazan ;Kazak, Canan ;Öztürk, Sema ;Zerrin, Caliskan ;Arsu, Nergis ;Fun, Hoong-Kun ;Erdönmez, Ahmet
- Book ID
- 104479714
- Publisher
- International Union of Crystallography
- Year
- 2002
- Tongue
- English
- Weight
- 159 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
The molecule of the title compound, C 19 H 23 NO, contains two phenyl rings and a piperidinyl ring. The dihedral angle between the phenyl rings is 40.99 (5) . The piperidine ring has a chair conformation. There is an intramolecular OÐHÁ Á ÁN hydrogen bond.
📜 SIMILAR VOLUMES
The title compound, C 18 H 18 O 3 , was synthesized with pure optically active reagents. The molecules possess two chiral atoms and are linked through O-HÁ Á ÁO hydrogen bonds in the crystal structure.
The lipase TL ® -mediated kinetic resolution of (±)-benzoin (1) proceeded to give the corresponding optically pure benzoin (R)-1. On the other hand, (S)-benzoin-O-acetate (5) could be hydrolyzed without epimerization to give (S)-benzoin (S)-1, under alkaline conditions. Further, (R)-1 was converted
In the crystals of the title compound, C 19 H 24 O 8 , the molecules adopt a conformation in which the bulky 2,6-dimethoxyphenoxy and 4-hydroxy-3,5-dimethoxyphenyl groups are distant from each other. The O(phenoxy)ÐCÐCÐC(phenyl) torsion angle between these groups is À177.27 (10) . The conformation i
## Abstract (R)‐(−) Benzoin oxime **2** was catalytically tritiated to afford [2‐^3^H] (1R,2S)‐(−)‐2‐amino‐1,2‐diphenylethanol **1** in 92% ee. Copyright © 2001 John Wiley & Sons, Ltd.