Erysipelothrix endocarditis affecting a porcine xenograft heart valve
β Scribed by Laurence J.H.E. Hayek
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 151 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0163-4453
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## Abstract Concerns with the currently available bioprostheses are calcification, longβterm durability, and suboptimal hemodynamic performance. It is well known that these concerns are all more or less related to the crossβlinking reagent, glutaraldehyde or formaldehyde, used in fixing bioprosthes
Calcification limits the long-term durability of xenograft glutaraldehyde-crosslinked heart valves. In this study, epoxy-crosslinked porcine aortic valve tissue was evaluated after subcutaneous implantation in weanling rats. Non-crosslinked valves and valves crosslinked with glutaraldehyde or carbod