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Error-prone replication of ultraviolet-irradiated Simian Virus 40 in carcinogen-treated monkey kidney cells

✍ Scribed by Sarasin, Alain; Bourre, François; Benoit, Annie

Book ID
122784317
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
995 KB
Volume
64
Category
Article
ISSN
0300-9084

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✍ Cornelis, Jan J. ;Rommelaere, Jean 📂 Article 📅 1985 🏛 Springer 🌐 English ⚖ 539 KB

Simian virus 40 (SV40) was used to probe ultraviolet light (UV)-induced mutation in mammalian cells. Viral mutations were scored as reversions of early and late temperature-sensitive (ts) mutants to the wild-type (WT) phenotype. When virus was exposed to moderate or high UV doses, WT revertants were