DHPLC is superior to SSCP in screening p
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Osamu Yamanoshita; Takeo Kubota; Jun Hou; Yu-Min Ping; Xiu-Lan Zhang; Xiang-Ping
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Article
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2005
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John Wiley and Sons
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French
⚖ 109 KB
Mutations of the p53 tumor-suppressor gene universally occur on exons 5-8 in human cancer. We analyzed these mutations in esophageal cancer tissue from 207 patients in China using 2 methods, single-strand conformation polymorphism (SSCP), one of the most frequently used methods, and the recently dev