Erratum to: Cardiotrophin 1 protects beta cells from apoptosis and prevents streptozotocin-induced diabetes in a mouse model
✍ Scribed by M. Jiménez-González, F. Jaques, S. Rodríguez, A. Porciuncula…
- Book ID
- 120906462
- Publisher
- Springer
- Year
- 2013
- Tongue
- English
- Weight
- 55 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0012-186X
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The development of diabetes in non-obese diabetic (NOD) mice, which normally takes between 3 and 7 months, can be accelerated by cyclophosphamide (CY) injections, with rapid progression to diabetes within only 2±3 weeks. This insulin-dependent diabetes mellitus (IDDM) can be prevented or delayed in
## Aims/hypothesis Carbohydrate-free diet prevents hyperglycaemia and beta cell destruction in the New Zealand Obese (NZO) mouse model. Here we have used a sequential dietary regimen to dissociate the effects of obesity and hyperglycaemia on beta cell function and integrity, and to study glucose-in