Erratum: The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide gliftor: The potential of 4-methylpyrazole as an antidote

The biochemical toxicology of 1,3-difluo

The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide Gliftor: The potential of 4-methylpyrazole as an antidote

✍ M. G. Feldwick; P. S. Noakes; U. Prause; R. J. Mead; P. J. Kostyniak 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB 👁 1 views

Administration to rats of 1,3-difluoro-2-propanol (100 mg kg-1 body weight), the major ingredient of the pesticide gliftor, resulted in accumulation of citrate in the kidney after a 3 hour lag phase. 1,3-Difluoro-2-propanol was found to be metabolized to 1,3-difluoroacetone and ultimately to the aco