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Erratum: Phosphatidylinositol 4,5-bisphosphate (PIP2)-specific AKT1 is oncogenic

Book ID
102272001
Publisher
John Wiley and Sons
Year
2012
Tongue
French
Weight
425 KB
Volume
130
Category
Article
ISSN
0020-7136

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✦ Synopsis

Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity

πŸ“œ SIMILAR VOLUMES

Phosphatidylinositol 4,5-bisphosphate-sp
Phosphatidylinositol 4,5-bisphosphate-specific AKT1 is oncogenic
✍ Nadine Dannemann; Jonathan Ross Hart; Lynn Ueno; Peter K. Vogt πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 406 KB

## Abstract The protein kinase AKT1 (v‐akt murine thymoma viral oncogene homolog 1), also referred to as protein kinase B (PKB), is an essential mediator of the phosphatidylinositol 3‐kinase signaling pathway. Elevated activity of AKT1 is common in human cancer. Localization at the plasma membrane,