Multivalent cations depress ligand affin
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Rebecca L. Sackett; Robert H. McCusker
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Article
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1998
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John Wiley and Sons
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English
⚖ 232 KB
👁 1 views
The effect of multivalent cations on [ 125 I]-IGF binding to cell-associated IGFBPs was investigated using human fibroblasts. The major cell-associated binding site for [ 125 I]-IGF-I is IGFBP-3 and for [ 125 I]-IGF-II are IGFBP-3 and IGFBP-5. Lanthanum and chromium did not affect either [ 125 I]-IG