Alzheimer amyloid aβ1–42 channels: Effec
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Yutaka Hirakura; Meng-Chin Lin; Bruce L. Kagan
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Article
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1999
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John Wiley and Sons
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English
⚖ 126 KB
Substantial genetic and biochemical evidence implicates amyloid peptides (A) in the etiology of Alzheimer's Disease (AD). Recent evidence indicates that A1-42 is the predominant species in the hallmark senile amyloid plaque of AD. Furthermore, A1-42 forms aggregates inside lysosomes of cultured n