High-resolution calorimetric and optical
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Jens Völker; R. D. Blake; Scott G. Delcourt; Kenneth J. Breslauer
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Article
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1999
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Wiley (John Wiley & Sons)
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English
⚖ 160 KB
We demonstrate that differential scanning calorimetry (DSC) can be used to yield high-resolution melting profiles for DNA plasmids that agree in all major features with the corresponding plasmid melting profiles derived using more traditional optical techniques. We further demonstrate that by combin