Cucurbitacin B suppresses the transactiv
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Hong Ri Jin; Xuejun Jin; Nguyen Tien Dat; Jung Joon Lee
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Article
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2011
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John Wiley and Sons
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English
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Cucurbitacin B, a natural triterpenoid is well-known for its strong anticancer activity, and recent studies showed that the compound inhibits JAK/STAT3 pathway. In this study, we demonstrate for the first time that cucurbitacin B is also a potent inhibitor of NF-kB activation. Our results showed tha