Erratic patient compliance with prescribed drug regimens: Target for drug delivery systems

Contending paradigms for the interpretat

Contending paradigms for the interpretation of data on patient compliance with therapeutic drug regimens

✍ John Urquhart; Erik De Klerk 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB 👁 1 views

Electronic and chemical marker methods provide the first reliable measurements of drug exposure in ambulatory trials. These data contradict the usual claim in published drug trials of '90% of patients having been satisfactorily compliant with the protocol-specified dosing regimen. Such exaggerated c