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ERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity

✍ Scribed by Kai He; Elias Aizenman


Book ID
111184023
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
581 KB
Volume
114
Category
Article
ISSN
0022-3042

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## Abstract Recent studies have shown that MEK/ERK‐mediated signals play a major role in regulation of activity of p53 tumor suppressor protein. In this study, we investigated whether or not there is functional interaction between p53 and MEK/ERK pathways in epithelial breast cancer cells exposed t