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ERK inhibitor PD98059 promotes the phenotypic and functional maturation of murine resident Langerhans cells

✍ Scribed by Hideki FUJITA; Akihiko ASAHINA; Mayumi KOMINE; Kunihiko TAMAKI


Book ID
108576278
Publisher
John Wiley and Sons
Year
2007
Tongue
French
Weight
97 KB
Volume
34
Category
Article
ISSN
0385-2407

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## Abstract ## Background Gene delivery in dendritic cells (DC) has raised considerable interest to modulate DC functions and induce therapeutic immunity or tolerance in an antigen‐specific fashion. Among immature DC, Langerhans cells (LC) are attractive candidates for antigen delivery using lenti