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Ergolide, sesquiterpene lactone from Inula britannica, inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB

✍ Scribed by Jeung Whan Han; Byeong Gon Lee; Yong Kee Kim; Jong Woo Yoon; Hye Kyoung Jin; Sungyoul Hong; Hoi Young Lee; Kang Ro Lee; Hyang Woo Lee

Book ID
110005721
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
297 KB
Volume
133
Category
Article
ISSN
0007-1188

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Dioscorealide B suppresses LPS-induced n
Dioscorealide B suppresses LPS-induced nitric oxide production and inflammatory cytokine expression in RAW 264.7 macrophages: The inhibition of NF-κB and ERK1/2 activation
✍ Poonsit Hiransai; Suvina Ratanachaiyavong; Arunporn Itharat; Potchanapond Graidi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB

## Abstract Dioscorealide B (DB), a naphthofuranoxepin has been purified from an ethanolic extract of the rhizome of __Dioscorea membranacea__ Pierre ex Prain & Burkill which has been used to treat inflammation and cancer in Thai Traditional Medicine. Previously, DB has been reported to have anti‐i