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Erbstatin blocks platelet activating factor-induced protein-tyrosine phosphorylation, polyphosphoinositide hydrolysis, protein kinase C activation, serotonin secretion and aggregation of rabbit platelets

โœ Scribed by Hassan Salari; Vincent Duronio; Sandra L. Howard; Michelle Demos; Kelvin Jones; Anne Reany; Alan T. Hudson; Steven L. Pelech


Book ID
115923528
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
590 KB
Volume
263
Category
Article
ISSN
0014-5793

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Previously we showed a rapid and transient inhibition of gap junctional communication (GJC) by platelet-derived growth factor (PDGF) in T51B rat liver epithelial cells expressing wild-type platelet-derived growth factor b receptors (PDGFrb). This action of PDGF correlated with the hyperphosphorylati