Equivalence of Prospective and Retrospective Models in the Bayesian Analysis of Case-Control Studies
✍ Scribed by Shaun R. Seaman and Sylvia Richardson
- Book ID
- 124304900
- Publisher
- Oxford University Press
- Year
- 2005
- Tongue
- English
- Weight
- 154 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0006-3444
- DOI
- 10.2307/20441206
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## Abstract We compare bias and power of three methods for haplotype inference on disease risk using unphased genotype data from a case‐control study. We examine the prospective score test of Schaid et al. ([2002] Am. J. Hum. Genet 70:425–434), a novel modification of the prospective estimating equ
## Abstract Penalized likelihood methods have become increasingly popular in recent years for evaluating haplotype‐phenotype association in case‐control studies. Although a retrospective likelihood is dictated by the sampling scheme, these penalized methods are typically built on prospective likeli