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Equivalence between Haseman-Elston and Variance-Components Linkage Analyses for Sib Pairs

โœ Scribed by P.C. Sham; S. Purcell


Book ID
119770010
Publisher
American Society of Human Genetics
Year
2001
Tongue
English
Weight
694 KB
Volume
68
Category
Article
ISSN
0002-9297

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## Abstract Existing standard methods of linkage analysis for quantitative phenotypes rest on the assumptions of either ordinary least squares (Haseman and Elston [1972] Behav. Genet. 2:3โ€“19; Sham and Purcell [2001] Am. J. Hum. Genet. 68:1527โ€“1532) or phenotypic normality (Almasy and Blangero [1998