Equilibrium centrifugation studies of colon DNA from mice treated with the carcinogen 1,2-dimethylhydrazine
โ Scribed by A. Hawks; E. Farber; P.N. Magee
- Book ID
- 113135280
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- English
- Weight
- 279 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0009-2797
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๐ SIMILAR VOLUMES
## Abstract DNA singleโstrand breaks induced in various organs of BALB/c mice by treatment with a single dose of 1,2โdimethylhydrazine (DMH) were studied by means of the alkaline elution method modified in order to allow the evaluation of DNA damage __in vivo__ with no need of radioactive prelabell
The host-mediated assay (HMA) was used to determine the spectra of mutations induced in the lacl gene of Escherichia coli cells recovered from the livers of Swiss mice exposed to the carcinogens 1,2-dimethylhydrazine (SDMH), azoxymethane (AOM), and methylazoxymethanolacetate (MAMA). These spectra we