Equilibria involved in the diorganotin(IV) and triorganotin(IV) phosphomycin interaction in aqueous solution

✍ Scribed by Girolamo Casella; Tiziana Fiore; Mahmoud M. A. Mohamed; László Nagy; Claudia Pellerito; Lorenzo Pellerito; Silvio Sammartano; Michelangelo Scopelliti

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 177 KB
• Volume: 21
• Category: Article
• ISSN: 0268-2605
• DOI: 10.1002/aoc.1220

✦ Synopsis

Abstract

The interaction of the dimethyltin(IV) and trimethyltin(IV) cations with the phosphomycin disodium salt, Na~2~[(1__R__, 2__S__)‐1,2‐epoxypropylphosphonate], has been investigated using potentiometric and UV–visible techniques at 25 °C and 0.1 M ionic strength (NaClO~4~) in aqueous solution. The species Me~2~SnLH^+^, Me~2~SnL, Me~2~SnL~2~^2−^, Me~2~SnLOH^−^ and Me~2~SnL(OH)~2~^2−^ (L = phosphomycinate^2−^) for dimethyltin(IV)–phosphomycinate, and the species Me~3~SnL^−^, and Me~3~SnLOH^2−^ for trimethyltin(IV)–phosphomycinate systems were considered. The protonation of the phosphomycinate^2−^ and formation constants of the complexes formed in solution were calculated using different computer programs. The speciation diagrams of the various complex species were evaluated as a function of pH. The involvement of different ligand functional groups in the binding to organotin(IV) is discussed. Copyright © 2007 John Wiley & Sons, Ltd.