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Epstein–Barr virus and plasmacytoid dendritic cells: A possible duet in autoimmunity

✍ Scribed by M. Severa; B. Serafini; V. Gafa; E. Anastasiadou; E. Giacomini; P. Trivedi; F. Aloisi; E.M. Coccia


Book ID
116399182
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
60 KB
Volume
48
Category
Article
ISSN
1043-4666

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Chronic evolution of acute hepatitis C (aHC) occurs in more than 80% of patients but can frequently be prevented by early treatment with interferon (IFN)-alpha. Plasmacytoid dendritic cells (pDCs) are the major endogenous IFN-alpha producers, but their role in aHC is unknown. In this study, frequenc