## Abstract Peripheral blood lymphocytes from normal seropositive donors and renal transplant recipients on various immunosuppressive regimens have been tested for their ability to mount a cytotoxic response when cultured with autologous EB virusβinfected B cells and thereby to cause regression of
EPSTEIN-BARR-VIRUS-SPECIFIC T-CELL MEMORY IN RENAL-ALLOGRAFT RECIPIENTS UNDER LONG-TERM IMMUNOSUPPRESSION
β Scribed by Gaston, J.S.H.; Rickinson, A.B.; Epstein, M.A.
- Book ID
- 122917746
- Publisher
- The Lancet
- Year
- 1982
- Tongue
- English
- Weight
- 463 KB
- Volume
- 319
- Category
- Article
- ISSN
- 0140-6736
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## Abstract Four indlces of the EB virus carrier state, for which quantitative __in vitro__ assays now exist, have been monitored in 55 renal allograft recipients under longβterm immunosuppression, each patient being tested on a single occasion. By comparison with parallel data from healthy control
## Abstract Under appropriate culture conditions, EB virus infection of lymphocytes from seropositive donors leads to regression of transformation, and this was shown previously to be due to activation in a secondary immune response of T lymphocytes inhibitory for the autologous lymphoblastoid cell