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Epstein-barr virus specific IgA serum antibodies in nasopharyngeal and other respiratory carcinomas

✍ Scribed by C. Desgranges; G. De-Thé

Publisher
John Wiley and Sons
Year
1979
Tongue
French
Weight
377 KB
Volume
24
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

In order to better understand the relationship between IgA and IgG antibodies to Epstein‐Barr virus (EBV) in nasopharyngeal carcinoma (NPC), we analyzed 230 NPC sera but also a series of sera from patients with other carcinomas selected for their high EBV/IgG antibody titres. We were surprised to find that 21 out of 46 sera from bronchopulmonary carcinomas (BPC) and 6 out of 7 carcinomas of nasal fossae were IgA anti‐VCA positive, and 9 BPC sera and 5 nasal fossae sera were also positive for IgA anti‐EA. Bronchial undifferentiated small‐cell carcinomas may represent a particular group associated with high EBV profile.

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