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Epitope Studies with Anti-β2-glycoprotein I Antibodies from Autoantibody and Immunized Sources

✍ Scribed by Stephen W Reddel; Ying Xia Wang; Yong Hua Sheng; Steven A Krilis

Book ID: 115621780
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 127 KB
Volume: 15
Category: Article
ISSN: 0896-8411
DOI: 10.1006/jaut.2000.0427

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## Abstract ## Objective Results of previous studies suggest that anti–β~2~‐glycoprotein I (anti‐β~2~GPI) antibodies in complex with β~2~GPI activate platelets in a dysregulated manner, potentially contributing to the prothrombotic tendency associated with the antiphospholipid syndrome (APS). We u