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Epithelioid leiomyosarcoma of the larynx

✍ Scribed by Raj Sindwani; T. Wayne Matthews; Jane Thomas; Varagur M. Venkatesan

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 279 KB
Volume: 20
Category: Article
ISSN: 1043-3074
DOI: 10.1002/(sici)1097-0347(199809)20:6<563::aid-hed12>3.0.co;2-l

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✦ Synopsis

Background. Tumors of smooth muscle origin are rare in the upper aerodigestive tract, due to the paucity of smooth muscle in the area. A review of the literature revealed 34 reported cases of leiomyoma, 9 cases of leiomyosarcoma, and only 2 cases of epithelioid leiomyoma arising in the larynx.

Methods. A case report of an epithelioid leiomyosarcoma arising in the right piriform fossa of a 38-year-old man is presented.

Results. The tumor was treated with conservative surgical resection and postoperative radiotherapy. There was no evidence of locoregional recurrence 2 years postsurgery, and laryngeal function was preserved.

Conclusions. To our knowledge, this is the third case of a laryngeal epithelioid smooth muscle tumor to be reported in the world literature and the only documentation of an epithelioid leiomyosarcoma arising in the larynx.

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