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Epithelial–mesenchymal transition in cancer development and its clinical significance

✍ Scribed by Masaaki Iwatsuki; Koshi Mimori; Takehiko Yokobori; Hideshi Ishi; Toru Beppu; Shoji Nakamori; Hideo Baba; Masaki Mori

Book ID
108586592
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
359 KB
Volume
101
Category
Article
ISSN
1347-9032

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## Abstract Cancer stem cells (CSCs) are similar to normal stem cells in their ability to self‐renew and to generate large populations of more differentiated descendants. In contrast to the hierarchical organization that is presumed to be the prevalent mode of normal tissue homeostasis, phenotypic