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Epithelial nitric oxide expression in inflammatory bowel disease: An oxidative barrier of the inflammed mucosa?

โœ Scribed by Dijkstra, G.; van Dullemen, H.M.; Moshage, H.; de Jager-Krikken, A.; Tiebosch, A.T.M.G.; Jansen, P.L.M.; van Goor, H.


Book ID
123535220
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
140 KB
Volume
114
Category
Article
ISSN
0016-5085

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Expression of nitric oxide synthases and
โœ Dijkstra, Gerard; Moshage, Han; Van Dullemen, Hendrik M.; de Jager-Krikken, Alie ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 282 KB ๐Ÿ‘ 2 views

## Nitric oxide (NO) and reactive oxygen species (ROS) are important mediators in the pathogenesis of inflammatory bowel disease (IBD). NO in IBD can be either harmful or protective. NO can react with superoxide anions (O 2 โ€ข ), yielding the toxic oxidizing agent peroxynitrite (ONOO ). Peroxynitri