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Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4+CD25+ T cells

✍ Scribed by Sharmal Narayan; Allison Choyce; Richard Linedale; Nicholas A. Saunders; Alison Dahler; Emily Chan; Germain J. Fernando; Ian H. Frazer; Graham R. Leggatt


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
372 KB
Volume
39
Category
Article
ISSN
0014-2980

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✍ Johan W. Molling; Tanja D. de Gruijl; Judith Glim; Maria Moreno; Lawrence Rozend 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 291 KB

## Abstract CD4^+^CD25^hi^CTLA4^+^FoxP3^+^ regulatory T cells (Treg) have been shown to maintain immune tolerance against self antigens and increased circulating frequencies have been reported in various types of cancers. Circulating invariant natural killer T‐cells (iNKT) are reduced in cancer pat