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Episomally Mediated Overexpression of Wild-TypeerbB-2 Transforms MCF-10A Breast Epithelial Cells

✍ Scribed by Bennett W. Yu; Mark Bowers; Greg Witkowski; Meiyi Huang; Satyabama Ramachandran

Book ID
110401493
Publisher
Springer US
Year
2002
Tongue
English
Weight
654 KB
Volume
76
Category
Article
ISSN
0167-6806

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## Abstract To investigate the effects of cyclooxygenase‐2 (__COX‐2__) overexpression on breast cancer development, we stably transfected MCF‐10F human breast epithelial cells with an expression vector containing human __COX‐2__ cDNA oriented in the sense (10F‐S) or antisense (10F‐AS) direction. As