Epimorphin is involved in differentiation of rat hepatic stem-like cells through cell–cell contact
✍ Scribed by Kouichi Miura; Hirokazu Nagai; Yasuharu Ueno; Takashi Goto; Ken-ichiro Mikami; Kunio Nakane; Kazuo Yoneyama; Daisuke Watanabe; Kunihiko Terada; Toshihiro Sugiyama; Katsuyuki Imai; Haruki Senoo; Sumio Watanabe
- Book ID
- 116287284
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 424 KB
- Volume
- 311
- Category
- Article
- ISSN
- 0006-291X
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## Abstract The hepatic‐like phenotype resulting from in vitro differentiation of unrestricted somatic stem cells (USSC) derived from human umbilical cord blood (CB) was analyzed with regard to functional and metabolic aspects. USSC can be differentiated into cells of all three germ layers in vitro
## Abstract Epimorphin/syntaxin 2 is a high conserved and very abundant protein involved in epithelial morphogenesis in various organs. We have shown recently that epimorphin (EPM), a protein exclusively expressed on the surface of hepatic stellate cells and myofibroblasts of the liver, induces bil