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Epigenetics in Gastrointestinal Stromal Tumors: Clinical Implications and Potential Therapeutic Perspectives

✍ Scribed by Athanasios D. Sioulas, Diamantina Vasilatou, Vasiliki Pappa, George Dimitriadis, Konstantinos Triantafyllou

Book ID
120966733
Publisher
Springer US
Year
2013
Tongue
English
Weight
263 KB
Volume
58
Category
Article
ISSN
0163-2116

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## Abstract Germ‐line mutations in the __KIT__ receptor tyrosine kinase gene have been described in families with a propensity to develop gastrointestinal stromal tumor (GIST). There is limited information from large kindreds regarding median age at diagnosis, detailed histopathology, clinical effe