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Epigenetics in clinical practice: the examples of azacitidine and decitabine in myelodysplasia and acute myeloid leukemia

✍ Scribed by Estey, E H


Book ID
120660448
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
968 KB
Volume
27
Category
Article
ISSN
0887-6924

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Survivin, an inhibitor of apoptosis (IAP) protein plays a dual role in regulation of mitosis and inhibition of apoptosis. Survivin is expressed in embryonic and fetal organs as well as in most human cancers, but not in normal differentiated adult tissues. In this study we investigated the molecular