𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Epigenetic silencing of the integrin α4 gene by hypermethylation in pancreatic ductal adenocarcinoma

✍ Scribed by S. T. Martin; S. R. Hustinx; C. J. Yeo; R. H. Hruban; M. Goggins

Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
301 KB
Volume
174
Category
Article
ISSN
1863-4362

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Silencing of the retinoid response gene
Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma
✍ Joseph Kwong; Kwok-Wai Lo; Lillian Shuk-Nga Chow; Franky Leung Chan; Ka-Fai To; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 570 KB

## Abstract Tazarotene‐induced gene 1 (__TIG1__) and Tazarotene‐induced gene 3 (__TIG3__) are retinoid acid (RA) target genes as well as candidate tumor suppressor genes in human cancers. In our study, we have investigated the expression of __TIG1__ and __TIG3__ in nasopharyngeal carcinoma (NPC). L

Induction of osteopontin expression by n
Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells
✍ Galina Chipitsyna; Qiaoke Gong; Rathai Anandanadesan; Amer Alnajar; Surinder K. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 460 KB 👁 1 views

## Abstract Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with etiological association with cigarette smoking. Nicotine, an important component of cigarettes, exists at high concentrations in the bloodstream of smokers. Osteopontin (OPN) is a secreted phosphoprotein that confers on can

Epigenetic silencing of the imprinted ge
Epigenetic silencing of the imprinted gene ZAC by DNA methylation is an early event in the progression of human ovarian cancer
✍ Tetsuya Kamikihara; Takahiro Arima; Kiyoko Kato; Takao Matsuda; Hidenori Kato; T 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 610 KB

## Abstract __ZAC__ is a paternally expressed, imprinted gene located on chromosome 6q24, within a region known to harbor a tumor suppressor gene for several types of neoplasia, including human ovarian cancer (HOC). We have failed to identify genetic mutations in the __ZAC__ gene in tumor material.

Lack of allelic loss at the multiple end
Lack of allelic loss at the multiple endocrine neoplasia type 1(MEN-1) gene locus in a pancreatic ductal (non-endocrine) adenocarcinoma of a patient with the MEN-1 syndrome
✍ Cesare Bordi; Cinzia Azzoni; Tiziana D'Adda; Anacleto Peracchia; Alberto Falchet 📂 Article 📅 1995 🏛 Springer 🌐 English ⚖ 951 KB

The gene responsible for multiple endocrine neoplasia type I (MEN-l) syndrome has been mapped to chromosome l lq13. It appears to function as a tumoursuppressor gene analogous to that for retinoblastoma and allelic losses involving the wild-type of the MEN-1 allele have been found in parathyroid and

Sensitive detection of loss of heterozyg
Sensitive detection of loss of heterozygosity in the TP53 gene in pancreatic adenocarcinoma by fluorescence-based single-strand conformation polymorphism analysis using blunt-end DNA fragments
✍ Kokichi Sugano; Yuki Nakashima; Kensei Yamaguchi; Noriko Fukayama; Masato Maekaw 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 590 KB

We have developed a fluorescence-based single-strand conformation polymorphism analytis to detect Haelll-sensitive polymorphic sites in intron I of the 7/53 gene. It is important t o treat the PCR products with Klenow fragment t o remove a 3'-protruding nucleotide from the amplified DNA fragments ad