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Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells

โœ Scribed by Makoto Osanai; Masaki Murata; Hideki Chiba; Takashi Kojima; Norimasa Sawada

Book ID
108583976
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
238 KB
Volume
98
Category
Article
ISSN
1347-9032

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## Abstract Survivin is recognized as an attractive target in cancer therapy because of its selective overexpression in the majority of tumors. Upregulated expression of this protein correlates with increased tumor grade, recurrence risk and decreased cancer patients survival. In this study, we ass