Epigenetic regulation of the imprinted U2af1-rs1 gene during retinoic acid-induced differentiation of embryonic stem cells

Identification of a Cis-acting element i

Identification of a Cis-acting element in the rat α-fetoprotein gene and its specific binding proteins in F9 cells during retinoic acid-induced differentiation

✍ Hongmin Chen; Jing-Ming Dong; Yi Liu; Jen-Fu Chiu 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB 👁 1 views

Mouse F9 embryonic teratocarcinoma stem cells can be induced to differentiate into visceral endoderm. Following retinoic acid (RA) treatment, alpha-fetoprotein (AFP), a differentiation marker, is expressed and secreted. The mechanism by which RA regulates AFP expression during differentiation is not