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Epigenetic regulation of caspase-3 gene expression in rat brain development

✍ Scribed by Alexander Yakovlev; Maryam Khafizova; Ziedulla Abdullaev; Dmitri Loukinov; Alexei Kondratyev

Book ID: 116508319
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 808 KB
Volume: 450
Category: Article
ISSN: 0378-1119
DOI: 10.1016/j.gene.2009.10.008

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## Abstract Recent studies indicate that caspase‐3 has distinct characteristics in postmitotic and neuronal progenitor apoptosis. Pyramidal neurons in CA1 and CA3 of the hippocampus become postmitotic during early postnatal development, whereas granule cells in the dentate gyrus (DG) undergo self‐r