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Epigenetic regulation of antigen receptor rearrangement

✍ Scribed by Matthew Inlay; Yang Xu


Book ID
117792974
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
102 KB
Volume
109
Category
Article
ISSN
1090-2341

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Two specialized forms of site-directed double-strand (ds) DNA breakage and rejoining are part of the physiologic program of lymphocytes. One is recombination of the V, D and J gene sequences, termed V(D).I recombination, occurring during early B-and T-cell development, and the other is class switch