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Epigenetic regulation in RCC: opportunities for therapeutic intervention?

✍ Scribed by Larkin, James; Goh, Xin Yi; Vetter, Marcus; Pickering, Lisa; Swanton, Charles

Book ID: 111869230
Publisher: Nature Publishing Group
Year: 2012
Tongue: English
Weight: 773 KB
Volume: 9
Category: Article
ISSN: 1759-4812
DOI: 10.1038/nrurol.2011.236

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## Abstract Epigenetics is concerned about heritable changes in gene expression without alteration of the coding sequence. Epigenetic modification of chromatin includes methylation of genomic DNA as well as post‐translational modification of chromatin‐associated proteins, in particular, histones. T