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Epigenetic inactivation of PCDH10 in human prostate cancer cell lines

โœ Scribed by Li, Zesong; Li, Wenjie; Xie, Jun; Wang, Yong; Tang, Aifa; Li, Xianxin; Ye, Jiongxian; Gui, Yaoting; Cai, Zhiming

Book ID
119739760
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
214 KB
Volume
35
Category
Article
ISSN
1065-6995

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## Abstract Lipoprotein lipase (__LPL__) is in chromosome 8p22, site of one of the most common somatic deletions in prostate tumors. Additionally, a CpG island (CGI) was identified in the __LPL__ promoter region. To test the hypothesis that __LPL__ is a tumor suppressor gene, which is inactivated b