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Epigenetic changes related to beta-amyloid-implications for Alzheimer's disease

✍ Scribed by Christina Unger Lithner; Caterina M. Hernandez; Agneta Nordberg; J. David Sweatt

Book ID
118465061
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
44 KB
Volume
5
Category
Article
ISSN
1552-5260

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## Abstract Amyloid beta protein (Aβ)‐related death‐inducing protein (AB‐DIP) is a novel Aβ binding protein expressed ubiquitously. Here we demonstrate that overexpression of AB‐DIP in SH‐SY5Y neuroblastoma cells causes G2/M arrest. By deletion mutant analysis, we have identified the minimal region