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Epigenetic changes in the repression and induction of asparagine synthetase in human leukemic cell lines

✍ Scribed by Ding, Y; Li, Z; Broome, J D

Book ID
110056162
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
201 KB
Volume
19
Category
Article
ISSN
0887-6924

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## Abstract Treatment of CEM‐C7 cells with glucocorticoids produces a 2.5‐fold increase in the activity of the enzyme glutamine synthetase (GS). This increase is specific for steroids with glucocorticoid activity and occurs over a range of steroid concentrations consistent with a receptor‐mediated