✦ LIBER ✦

Epigenetic aspects of genotoxic and non-genotoxic hepatocarcinogenesis: Studies in rodents

✍ Scribed by Igor P. Pogribny; Ivan Rusyn; Frederick A. Beland

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 168 KB
Volume: 49
Category: Article
ISSN: 0893-6692
DOI: 10.1002/em.20342

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Epigenetics and Human Health (Linking He

Epigenetics and Human Health (Linking Hereditary, Environmental and Nutritional Aspects) || Genotoxic, Non-Genotoxic and Epigenetic Mechanisms in Chemical Hepatocarcinogenesis

✍ Haslberger, Alexander G. 📂 Article 📅 2010 🏛 Wiley-VCH Verlag GmbH & Co. KGaA 🌐 German ⚖ 155 KB

The Research Program In Epigenetics: The Birth Of A New Paradigm / Paolo Vineis -- Interactions Between Nutrition And Health / Ibrahim Elmadfa -- Epigenetics: Comments From An Ecologist / Fritz Schiemer -- Interaction Of Hereditary And Epigenetic Mechanisms In The Regulation Of Gene Expression / Tha

Reprotoxic and genotoxic studies of vana

Reprotoxic and genotoxic studies of vanadium pentoxide in male mice

✍ M. Altamirano-Lozano; L. Alvarez-Barrera; F. Basurto-Alcántara; M. Valverde; E. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 815 KB

Effects of vanadium pentoxide (V205) treatment on reproductive function and testicular DNA in male mice were investigated. These functions were evaluated with fertility rate, implants, resorptions, sperm counts, motility, and morphology. The DNA damage in individual testis cells was analyzed by sing

Prediction of rodent carcinogenicity uti

Prediction of rodent carcinogenicity utilizing a battery of in vitro and in vivo genotoxicity tests

✍ Byung Soo Kim; Barry H. Margolin 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 58 KB 👁 2 views

The primary purpose of this study is to investigate the degree to which we can improve the prediction of rodent carcinogenicity (CA) by combining results from an in vitro and two in vivo genotoxicity tests. We used the Ames Salmonella assay (SAL) for the in vitro test and the micronucleus assay (MNC

Examination of the potential genotoxicit

Examination of the potential genotoxicity of pure capsaicin in bacterial mutation, chromosome aberration, and rodent micronucleus tests

✍ Raymond Proudlock; Crista Thompson; Eric Longstaff 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 84 KB

Human relevance of rodent prolactin-indu

Human relevance of rodent prolactin-induced non-genotoxic mammary carcinogenesis: prolactin involvement in human breast cancer and significance for toxicology risk assessments

✍ Philip W. Harvey 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 64 KB 👁 1 views

Prolactin-induced mammary carcinogenesis in rodents, particularly rats, is often stated to be of low toxicological relevance to humans. This opinion appears to have developed from a number of lines of cited evidence. Firstly, there had been long experience of use of dopamine antagonists (that increa

Detoxification of aristolochic acid I by

Detoxification of aristolochic acid I by O-demethylation: Less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents

✍ Shinya Shibutani; Radha R. Bonala; Thomas Rosenquist; Robert Rieger; Naomi Suzuk 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 421 KB

## Abstract Ingestion of aristolochic acids (AA) contained in herbal remedies results in aristolochic acid nephropathy (AAN), which is characterized by chronic renal failure, tubulointerstitial fibrosis and urothelial cancer. AA I and AA II, primary components in AA, have similar genotoxic potentia