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Epigenetic and Genetic Alterations in Netrin-1 Receptors UNC5C and DCC in Human Colon Cancer

โœ Scribed by Sung Kwan Shin; Takeshi Nagasaka; Barbara H. Jung; Nagahide Matsubara; Won Ho Kim; John M. Carethers; C. Richard Boland; Ajay Goel


Book ID
119760049
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
657 KB
Volume
133
Category
Article
ISSN
0016-5085

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## Abstract The __MLH1__ โˆ’93 G>A promoter polymorphism has been reported to be associated with an increased risk of microsatellite unstable colorectal cancer. Other than microsatellite instability, however, the genetic and most epigenetic changes of tumors associated with this polymorphism have not