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Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies

✍ Scribed by John Mascarenhas; Nitin Roper; Pratima Chaurasia; Ronald Hoffman


Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
410 KB
Volume
2
Category
Article
ISSN
1868-7075

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✍ Pedro A. Lazo; Claudio R. Santos πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 271 KB

## SUMMARY Viral infections cause a major stress in host cells. The cellular responses to stress are mediated by p53, which by deregulation of cell cycle and apoptosis, may also be part of the host cell reaction to fight infections. Therefore, during evolutionary viral adaptation to host organisms,