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Epigallocatechin gallate promotes GLUT4 translocation in skeletal muscle

✍ Scribed by Manabu Ueda; Shin Nishiumi; Hironobu Nagayasu; Itsuko Fukuda; Ken-ichi Yoshida; Hitoshi Ashida

Book ID
116297526
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
245 KB
Volume
377
Category
Article
ISSN
0006-291X

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## Abstract Metformin is a major oral anti‐diabetic drug and is known as an insulin sensitizer. However, the mechanism by which metformin acts is unclear. In this study, we found that AICAR, an AMPK activator, and metformin increased the expression of Rab4 mRNA and protein levels in skeletal muscle