We have investigated the role of autocrine/paracrine TGF-b secretion in the regulation of cell growth by androgens as demonstrated by its inhibition by two androgen response modifiers; the nonsteroidal antiandrogen hydroxyflutamide (OHF), believed to act by inhibiting androgen binding to androgen re
โฆ LIBER โฆ
Epigallocatechin-3-gallate and bicalutamide cause growth arrest and apoptosis in NRP-152 and NRP-154 prostate epithelial cells
โ Scribed by Colm Morrissey; Mark Brown; Jacintha O'Sullivan; Natalie Weathered; R. William G. Watson; Martin Tenniswood
- Book ID
- 108977461
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 725 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0919-8172
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Retinoids and vitamin D analogues are known to inhibit the proliferation of a variety of cells in culture and prevent the formation of certain tumors in mammals. Although it is well established that these hormones control the transcription of many genes upon binding to and activating specific nuclea