Epidural granulocytic sarcoma in acute myeloid leukemia with 8;21 translocation
β Scribed by M. A. Wodzinski; R. Collin; D. A. Winfield; A. Dalton; A. C. K. Lawrence
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 217 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0008-543X
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## Background: Granulocytic sarcomas (gs) have been associated with t(8;21). the prognosis of patients with gs is generally regarded as being less favorable than of patients with acute myeloblastic leukemia (aml). gs occurs relatively commonly in africa and has been reported to affect 10-25% of bla
Cases of secondary acute myeloid leukemia (AML) occurring after treatment for an Ewing's sarcoma are uncommon. Therapy-related AML with t(8;21) translocation is an entity which has been well characterized. A case of AML-2 with t(8;21) and t(3;15) occurring 4 years after treatment for an Ewing's sarc
Three childhood acute monoblastic leukemias (AML M5) with granulocytic sarcomas (GSs) are described. All displayed 11q23/MLL abnormalities, t(9;11)(p22;q23) in two cases and t(11;17)(q23;q21) in one case, constituting around 20% of all 11q23-positive AML cytogenetically investigated in our departmen